منابع مشابه
Pathogenesis of meningococcemia.
Neisseria meningitidis is responsible for two major diseases: cerebrospinal meningitis and/or septicemia. The latter can lead to a purpura fulminans, an often-fatal condition owing to the associated septic shock. These two clinical aspects of the meningococcal infection are consequences of a tight interaction of meningococci with host endothelial cells. This interaction, mediated by the type IV...
متن کاملMeningococcemia
A 31-year-old woman without history of systemic diseases presented to the emergency department with spiking fever, chills, generalized myalgia, severe epigastralgia, and watery diarrhea for 1 day. Flulike symptoms had been noted for several days. Progressive extension of petechiae skin purpura (Fig. 1) developed within 2–3 h upon arrival at the hospital. Low blood pressure persisted despite vig...
متن کاملFatal meningococcemia
Within the past six years, a case of bothWaterhouse-Freidrichsen Syndrome and fulminant meningococcemia have presented to Union Memorial Hospital. Both cases presented in markedly different fashions, differed in microbiologic serogrouping, showed minimal histopathologic similarities; however achieved ultimately the same outcome through two different pathological pathways. The following case rep...
متن کاملFulminant meningococcemia
A 23 year old Caucasian woman was admitted to a local emergency room after awakening with “bruises” and “red spots” scattered over her body associated with fever and rigors and dizziness. Upon arrival, she had no measurable blood pressure and a temperature of 40.2 C. Petechiae and purpurae were noted primarily over her trunk and extremities. A CBC revealed WBC 2700/mm with a manual differential...
متن کاملMyopericarditis as an Initial Presentation of Meningococcemia
From the Cardiovascular and Infectious Disease Divisions, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts. This work was supported in part by Grant 5432 HL-07049 from the National Heart, Lung, and Blood Institute, Bethesda, Maryland. Requests for reprints shuld be addressed to Dr. James M. Kirshenbaum, Cardiovascular Division, Brigham and W...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Perspectives in Medicine
سال: 2013
ISSN: 2157-1422
DOI: 10.1101/cshperspect.a012393